毫无效果háowúxiàoguǒMeanings1. to no avail2. achieving nothing3. totally ineffective4. to have no effect5. to fall flat (esp. of joke or speech that is completely ignored)Characters used毫hair无not效effect果fruitExamples1这些zhèxiē问题wèntí对duì我们wǒmen毫无效果háowúxiàoguǒ。These issues have no effect on us.