奈何
Meanings
1. to do something to sb
2. to deal with
3. to cope
4. how?
5. to no avail
Characters used
Examples1
虽 受 邀 参加 今晚 一个 精彩 万分 的 派对, 奈何 明日 不得不 打 起 精神 出席 会议, 只好 推辞 了。
I got an invitation to a party tonight that I know would be a lot of fun but I have to be in my best form for tomorrow's meeting so I had to turn it down.